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Pharmacol Ther 173:135145

[DOI] [PubMed] [Google Scholar] Locasale J.W., Grassian A.R., Melman T., Lyssiotis C.A., Mattaini K.R., Bass A.J., Heffron G., Metallo C.M., Muranen T., Sharfi H., et al

Exerts potent anti-inflammatory effects in the gut and CNS by modulating nitric oxide pathways and reducing pro-inflammatory cytokines, closely resembling the protective actions of the native gastric peptide in response to mucosal injury

The product supplied here is for laboratory and research use only and is not for diagnostic, therapeutic, or human use.

A 2025 meta-analysis of 16 studies involving 6,098 participants found no statistically significant difference between intramuscular, oral, and sublingual B12 supplementation routes (p=0.270)